Late Late Show passed away on Thursday evening just days short of his 14th birthday.
The dogs trainer Paul Hennessy, who nicknamed the dog Duke, confirmed that the greyhound, who won €157,000 in prize money for charity, had died.
"Duke was a real gentleman of a dog both as a racer and in his retirement. He pottered away here over the years doing his own thing, he hasnít had a lead on him in years and he was a pleasure to have".
Late Late Show, carrying the namesake of RTE's flagship chat show, ran in the name of the former host Pat Kenny.
He ran up a sequence of 16 wins in 2001 during which he won the Tote Gold Cup, the Easter Cup, the Guinness 600 and the Derby Trial Stake.
His last litter of pups were born three months ago.
The original plan in relation to Late Late Show was that the dog would be given as a prize to a member of the chat-show audience.
But RTE believed that the prize and the association with gambling could cause potential problems for the State broadcaster. It was decided at the last moment to gift the dog to Pat Kenny, and register it at his RTE Montrose address.
It was the start of an astonishing success story. Late Late Show proved to be one of the greatest greyhounds ever produced in this country.
The Irish Greyhound Board spotted the marketing potential and other high-profile personalities found themselves with a greyhound in their name - though none achieved the same level of success.
A dog named 'Charlie Bird' enjoyed some success representing the RTE Newsroom, while Micheal O Muircheartaigh was linked with'Radio Sport'.